Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025 · 系統性回顧＋統合分析（依標題推測）
Outcomes after multiligament knee injury worsen over time: A systematic review and meta-analysis
膝 · 多韌帶膝關節損傷
中文閱讀摘要
多韌帶膝傷術後功能隨時間逐年下降，2年約保留80-85%，且PCL相關傷勢預後較差。
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原始摘要
Purpose
Multiligament knee injuries (MLKIs) are devastating injuries that can have life-long consequences. A management plan requires the decision to perform surgery or not, timing of surgery, consideration of repair versus reconstruction, reconstruction technique and reconstruction graft choice. The purpose of this study was to analyze development of clinical outcomes of MLKIs over time at a minimum of 2 years of follow-up.
Methods
Four databases were queried for surgical outcome-based studies of MLKIs published from 01/2000 through 09/2022 with a minimum 2-year follow-up. Technique articles, nonoperative treatment, arthroplasty, pediatric and review articles were excluded. Study characteristics including design, number of patients, age, follow-up period, anatomical region and posterior-cruciate ligament (PCL)-based injury were collected. Primary outcomes were Lysholm, International Knee Documentation Committee (IKDC) outcome scores and Tegner activity score. Random-effects model analysis was performed.
Results
After the application of inclusion and exclusion criteria, 3571 patients in 79 studies were included in the analysis. The mean age at surgery was 35.6 years. The mean follow-up was 4.06 years (range 2-12.7). The mean Lysholm score at 2-year follow-up was 86.09 [95% confidence interval [CI]: 82.90-89.28], with a yearly decrease of -0.80 [95% CI: -1.47 -0.13], (p = 0.0199). The mean IKDC at 2 years was 81.35 [95% CI: 76.56-86.14], with a yearly decrease of -1.99 [95% CI: -3.14 -0.84] (p < 0.001). Non-PCL-based injuries had a higher IKDC 83.69 [75.55-91.82] vs. 75.00 [70.75-79.26] (p = 0.03) and Lysholm score 90.84 [87.10-94.58] versus 84.35 [82.18-86.52] (p < 0.01) than PCL-based injuries, respectively.
Conclusion
According to the present systematic review and meta-analysis of MLKIs with minimum 2-year follow-ups, the patients who suffered an MLKI can expect to retain around 80-85% of knee function at 2 years and can expect a yearly deterioration of knee function, depending on the score used. Inferior outcomes can be expected for PCL-based injuries at 2 years postoperative.
Level of evidence
Level IV meta-analysis.
至 Europe PMC 閱讀完整來源 ↗ · 擷取日期 2026-10-19
書目、來源與全文狀態
- DOI
- 10.1002/ksa.12442
- PMID／PMCID
- 39194423 / PMC11948183
- 作者
- Klasan A, Maerz A, Putnis SE, Ernat JJ, Ollier E, Neri T
- 首次發表日期
- 2024-08-28Europe PMC 提供，部分日期可能依年份或月份推定。
- 卷／期／頁碼或文章編號
- 33 ／ 4 ／ 1281-1298
- 書目來源與查核日期
- Europe PMC · 2026-10-19僅核對書目欄位與來源連結；不代表已評讀研究品質。
- 全文與授權
- 來源列有免費全文（查核 2026-10-19），未逐篇測試 PDF 下載。 來源授權標示：cc by。
可回溯引用
Klasan A, Maerz A, Putnis SE, Ernat JJ, Ollier E, Neri T. Outcomes after multiligament knee injury worsen over time: A systematic review and meta-analysis. Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA. 2025;33(4):1281-1298. PMID: 39194423. PMCID: PMC11948183. doi:10.1002/ksa.12442
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