Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2026 · 系統性回顧＋統合分析（依標題推測）
Substantial blood loss and transfusion burden after periacetabular osteotomy: Benchmark estimates from a systematic review and meta-analysis
髖與鼠蹊 · 髖關節發育不良
中文閱讀摘要
系統性回顧與統合分析顯示，PAO術後輸血率約16.2%，手術時間越長失血越多，為術中血液管理提供基準。
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原始摘要
Purpose
To establish pooled benchmark estimates for perioperative blood loss and transfusion burden after periacetabular osteotomy (PAO) and to explore potential study-level moderators across the available literature.
Methods
A systematic search of PubMed, Embase, Epistemonikos and CENTRAL was performed up to 30 March 2026. Prospective and retrospective primary clinical studies reporting at least one predefined perioperative blood management outcome after PAO were included. Outcomes comprised transfusion rate, units transfused, intraoperative blood loss, estimated blood loss, haemoglobin drop and postoperative haemoglobin levels. Random-effects meta-analyses of proportions and means were performed. Univariable meta-regression was used to explore study-level moderators.
Results
Forty-seven studies comprising 4402 patients and 4767 hips were included. The pooled transfusion rate was 16.2% (95% confidence interval [CI] = 11.1-23.0), and the pooled mean number of transfused units was 1.94 (95% CI = 1.32-2.55). The pooled mean intraoperative blood loss was 961.8 mL (95% CI = 804.1-1119.5), and the pooled mean estimated blood loss was 809.9 mL (95% CI = 706.4-913.5). The pooled mean haemoglobin drop was 32.4 g/L (95% CI = 27.7-37.1), and the pooled mean postoperative haemoglobin level was 99.4 g/L (95% CI = 97.2-101.6). Longer operative time was significantly associated with higher intraoperative and estimated blood loss. Higher preoperative haemoglobin was associated with greater haemoglobin drop, while higher age was associated with transfusion-related outcomes.
Conclusion
PAO is associated with substantial perioperative blood loss and a relevant transfusion burden. These pooled estimates provide clinically useful benchmark values for perioperative blood management after PAO.
Level of evidence
Level III systematic review and meta-analysis of predominantly retrospective cohort studies.
至 Europe PMC 閱讀完整來源 ↗ · 擷取日期 2026-10-19
書目、來源與全文狀態
- DOI
- 10.1002/ksa.70432
- PMID／PMCID
- 42233595 / PMC13327451
- 作者
- Ramadanov N, Lettner J, Becker R, Prill R, Ostojic M, Ahmad SS
- 首次發表日期
- 2026-06-03Europe PMC 提供，部分日期可能依年份或月份推定。
- 卷／期／頁碼或文章編號
- 34 ／ 7 ／ 2576-2601
- 書目來源與查核日期
- Europe PMC · 2026-10-19僅核對書目欄位與來源連結；不代表已評讀研究品質。
- 全文與授權
- 來源列有免費全文（查核 2026-10-19），未逐篇測試 PDF 下載。 來源授權標示：cc by。
可回溯引用
Ramadanov N, Lettner J, Becker R, Prill R, Ostojic M, Ahmad SS. Substantial blood loss and transfusion burden after periacetabular osteotomy: Benchmark estimates from a systematic review and meta-analysis. Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA. 2026;34(7):2576-2601. PMID: 42233595. PMCID: PMC13327451. doi:10.1002/ksa.70432
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