Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2026 · 系統性回顧＋統合分析（依標題推測）
Second ACL injuries in football players after ACL reconstruction: A systematic review and meta-analysis.
膝 · 前十字韌帶損傷
中文閱讀摘要
系統性回顧統合分析足球ACL重建後二次受傷，整體發生率21.6%，女性、年輕及重返運動者風險較高，但研究異質性大。
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原始摘要
Purpose
To determine the incidence of second anterior cruciate ligament (ACL) injuries in football players after index ACL reconstruction (ACLR). Secondary objectives were to assess second ACL injury rates across subgroups (laterality, sex, age, playing level, graft type, return to play [RTP] and follow-up duration) and to review factors associated with reinjury.
Methods
A systematic review and meta-analysis were conducted according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. PubMed, EMBASE and the Cochrane Library were searched from inception to 10 December 2025. Studies reporting second ACL injuries or subsequent ACLRs in football players were included. Incidence was defined as the proportion of players sustaining a subsequent ACL injury or ACLR relative to those undergoing index ACLR. RTP was defined as participation in at least one official match. Key limitations include substantial heterogeneity across studies, the inclusion of mixed data sources and the operational definition of second ACL injury, combining ACL injuries (graft rupture or contralateral tear) or, when not reported, subsequent ACLRs.
Results
Thirty-four studies (16,905 players; 50.5% male) were included. The pooled incidence of second ACL injury was 21.6% (95% confidence interval [CI] 17.9%-25.9%). Contralateral (10.6%, 95% CI 8.0%-13.9%) and ipsilateral injuries (10.4%, 95% CI 8.4%-12.9%) were of similar magnitude. Higher pooled incidence was observed in female (23.5%, 95% CI 18.0%-30.1%) compared with male players (14.5%, 95% CI 14.5%-23.4%), with 30% increased odds (odds ratio [OR] 1.3, 95% CI 1.1%-1.7%, p < 0.01). Among professionals, incidence was 19.2% (95% CI 15.1%-24.2%). No significant differences were found between hamstring tendon and bone-patellar tendon-bone (BPTB) autografts. The highest rates were observed in players <21 years (31.9%, 95% CI 23.6%-41.6%) and in cohorts with high RTP rates (29.2%, 95% CI 24.7%-34.1%).
Conclusion
Second ACL injuries are common in football, affecting roughly between one in three to one in five players after ACLR. Higher rates of second ACL injury were observed in female players, younger individuals, those who returned to play, and in studies with longer follow-up duration. Contralateral ACL injuries had a similar magnitude to ipsilateral injuries. No significant differences in ipsilateral ACL reinjury rates were found between hamstrings tendon and BPTB autografts.
Level of evidence
Level IV, systematic review and meta-analysis.
至 Europe PMC 閱讀完整來源 ↗ · 擷取日期 2026-10-19
書目、來源與全文狀態
- DOI
- 10.1002/ksa.70471
- PMID／PMCID
- 42233600
- 作者
- López Personat A, Mariscal G, Stålman A, Cristiani R, Von Essen C, Capurro-Soler B, Chahla J, Sandon A
- 首次發表日期
- 2026-06-03Europe PMC 提供，部分日期可能依年份或月份推定。
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- 卷未提供 ／ 期未提供 ／ 頁碼或文章編號未提供
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- Europe PMC · 2026-10-19僅核對書目欄位與來源連結；不代表已評讀研究品質。
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- 來源尚未確認免費全文。 來源授權標示：cc by。
可回溯引用
López Personat A, Mariscal G, Stålman A, Cristiani R, Von Essen C, Capurro-Soler B, Chahla J, Sandon A. Second ACL injuries in football players after ACL reconstruction: A systematic review and meta-analysis. Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA. 2026. PMID: 42233600. doi:10.1002/ksa.70471
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