European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026 · 系統性回顧＋統合分析（依標題推測）
Is therapeutic exercise as a standalone intervention effective in reducing kinesiophobia in adults with nonspecific chronic low back pain? A systematic review and meta-analysis with meta-regression
腰椎 · 下背痛
中文閱讀摘要
系統性回顧與統合分析顯示，獨立運動顯著降低非特異性慢性下背痛成人的運動恐懼，但證據確信度低且異質性高。
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原始摘要
Purpose
Kinesiophobia is a psychosocial factor associated with pain persistence and disability in individuals with nonspecific chronic low back pain (NSCLBP). Although exercise therapy is commonly recommended, its isolated effect on kinesiophobia remains unclear. This systematic review and meta-analysis aimed to evaluate the effectiveness of standalone exercise in reducing kinesiophobia in adults with NSCLBP.
Methods
A systematic search was conducted in MEDLINE, Cochrane Library, Web of Science, and Scopus without date or language restrictions. Randomized controlled trials including adults with NSCLBP (≥3 months) receiving standalone exercise were eligible. Risk of bias was assessed using the Cochrane Risk of Bias 2 tool, and certainty of evidence was evaluated using GRADE. Random-effects meta-analyses calculated mean differences (MD) and standardized mean differences (SMD). Meta-regression explored heterogeneity.
Results
Eight randomized controlled trials involving 854 participants were included. Studies presented some concerns regarding risk of bias, and certainty of evidence was rated as low. Standalone exercise significantly reduced kinesiophobia compared with passive controls and usual care (MD = -5.38; 95% CI -7.63 to -3.13; SMD = -1.03), exceeding the minimal clinically important difference. However, considerable heterogeneity was observed (I² ≈ 94%), and meta-regression did not identify significant moderators. These findings were exploratory and limited by the small number of studies.
Conclusion
Standalone exercise may reduce kinesiophobia in adults with NSCLBP; however, heterogeneity, methodological concerns, and low-certainty evidence limit confidence in the pooled effect estimate. Therefore, the observed effect should be interpreted as an overall trend rather than a consistent effect across populations and interventions.
至 Europe PMC 閱讀完整來源 ↗ · 擷取日期 2026-10-19
書目、來源與全文狀態
- DOI
- 10.1007/s00586-026-10365-w
- PMID／PMCID
- 42730933
- 作者
- Cardellat-González M, Moral-Munoz JA, Cuevas-Moreno A, González-Gómez L, Blanco-Heras L, Rodríguez-Domínguez ÁJ
- 首次發表日期
- 2026-09-12Europe PMC 提供，部分日期可能依年份或月份推定。
- 卷／期／頁碼或文章編號
- 卷未提供 ／ 期未提供 ／ 頁碼或文章編號未提供
- 書目來源與查核日期
- Europe PMC · 2026-10-19僅核對書目欄位與來源連結；不代表已評讀研究品質。
- 全文與授權
- 來源尚未確認免費全文。 來源授權標示：cc by。
可回溯引用
Cardellat-González M, Moral-Munoz JA, Cuevas-Moreno A, González-Gómez L, Blanco-Heras L, Rodríguez-Domínguez ÁJ. Is therapeutic exercise as a standalone intervention effective in reducing kinesiophobia in adults with nonspecific chronic low back pain? A systematic review and meta-analysis with meta-regression. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 2026. PMID: 42730933. doi:10.1007/s00586-026-10365-w
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