Sports medicine (Auckland, N.Z.) · 2026 · 系統性回顧＋統合分析（依標題推測）
Which Exercise Prescriptions Improve Physical Fitness in Patients with Breast Cancer Before, During, and Following Treatment? A Systematic Review and Meta-analysis of Randomized Controlled Trials
腫瘤運動復健 · 乳癌運動介入
中文閱讀摘要
統合分析顯示運動提升乳癌患者肌力與心肺適能，但效果隨治療階段與處方差異，監督式結合運動改善最顯著。
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原始摘要
Background
Exercise is now recognized as an essential component of the cancer care continuum. However, the optimal exercise prescriptions to improve physical fitness in breast cancer remain under debate.
Objectives
In a systematic review and meta-analysis of randomized controlled trials (RCTs), we investigated how exercise affects muscular strength, fat-free mass, functional exercise capacity (FEC) and cardiorespiratory fitness during pretreatment, active treatment, and post-treatment for breast cancer. We also investigated how exercise mode, frequency, intensity, supervision, and duration of intervention affect breast cancer survivors' physical fitness.
Methods
We searched four electronic databases to identify RCTs examining exercise's effects on muscular strength, fat-free mass, functional exercise capacity, FEC, and cardiorespiratory fitness in women with breast cancer. We calculated pooled effects (SMD) using the software Comprehensive Meta-Analysis. Subgroup analyses were conducted based on phases of cancer care and exercise mode, frequency, intensity, supervision, and duration of intervention.
Results
Across 68 randomized controlled trials (N = 4,158), exercise significantly increased muscular strength (Hedges' g = 0.66, 95% CI 0.46-0.85), FEC (Hedges' g = 1.04, 95% CI 0.56-1.52), cardiorespiratory fitness (Hedges' g = 0.96, 95% CI 0.45-1.47), and fat-free mass (Hedges' g = 0.12, 95% CI 0.03-0.20). However, these effects varied according to the phase of cancer care and exercise prescription characteristics, including modality, frequency, supervision, intensity, and duration. During active treatment, combined exercise significantly improved muscular strength, FEC, and cardiorespiratory fitness, but not fat-free mass. In contrast, post-treatment exercise significantly enhanced muscular strength, fat-free mass, and FEC, with no significant effect on cardiorespiratory fitness. Data for evaluating exercise's pretreatment effects were insufficient. The greatest improvements across outcomes were observed with supervised combined aerobic-resistance exercise programs performed at least three times per week for a minimum of 12 weeks.
Conclusions
Although exercise improves breast cancer survivors' physical fitness, its effects differ depending on its mode, frequency, intensity, supervision, and total duration in addition to the phase of cancer care.
至 Europe PMC 閱讀完整來源 ↗ · 擷取日期 2026-10-19
書目、來源與全文狀態
- DOI
- 10.1007/s40279-025-02390-4
- PMID／PMCID
- 41879915 / PMC13198464
- 作者
- Cassaroti VSS, Lopes MR, Palma GHD, Cella PS, Godinho LRLC, Azevedo TG, Nunes JHC, Borges MBS, Deminice R
- 首次發表日期
- 2026-03-25Europe PMC 提供，部分日期可能依年份或月份推定。
- 卷／期／頁碼或文章編號
- 56 ／ 5 ／ 1175-1190
- 書目來源與查核日期
- Europe PMC · 2026-10-19僅核對書目欄位與來源連結；不代表已評讀研究品質。
- 全文與授權
- 來源列有免費全文（查核 2026-10-19），未逐篇測試 PDF 下載。 來源授權標示：cc by。
可回溯引用
Cassaroti VSS, Lopes MR, Palma GHD, Cella PS, Godinho LRLC, Azevedo TG, Nunes JHC, Borges MBS, Deminice R. Which Exercise Prescriptions Improve Physical Fitness in Patients with Breast Cancer Before, During, and Following Treatment? A Systematic Review and Meta-analysis of Randomized Controlled Trials. Sports medicine (Auckland, N.Z.). 2026;56(5):1175-1190. PMID: 41879915. PMCID: PMC13198464. doi:10.1007/s40279-025-02390-4
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