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Geriatric nursing (New York, N.Y.) · 2026 · 系統性回顧(依標題推測)

Effectiveness of physical exercise on osteosarcopenia in older adults: A systematic review.

高齡・肌少・骨骼健康 · 肌少症

中文閱讀摘要

系統性回顧僅含四項研究,顯示阻力訓練可提升肌力與肌肉量,但未顯著改善體能,因證據有限難以定論。

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原始摘要

Background

Osteosarcopenia is a geriatric syndrome characterized by the coexistence of sarcopenia and osteopenia/osteoporosis, which can lead to frailty and mortality. The effectiveness of physical exercise on osteosarcopenia, particularly on muscular and skeletal parameters, remains unclear. This systematic review aimed to analyze the impact of exercise interventions on osteosarcopenia in older adults and to describe the diagnostic methods used in different clinical trials.

Methods

Randomized clinical trials conducted in older adults (≥65 years) diagnosed with osteosarcopenia were included, sourced from PubMed, Embase, Cochrane, and Scopus databases without language or publication year restrictions, up to July 2024. Osteosarcopenia was defined as the coexistence of sarcopenia and osteopenia/osteoporosis based on dual-energy X-ray absorptiometry (DXA) criteria. Exercise interventions of at least four weeks were considered, with comparisons to non-exercise control groups. This systematic review followed the PRISMA guidelines and was registered in PROSPERO (CRD42016043310).

Results

A total of 250 articles were identified, but only four studies met the eligibility criteria, involving 195 participants. All included studies utilized resistance training (RT) as the exercise intervention. The most common diagnostic criteria for osteosarcopenia were based on the T-score of the lumbar spine and/or femur, measured via DXA, using World Health Organization cut-off points for bone mineral density (BMD) and the criteria from the European Working Group on Sarcopenia in Older People for sarcopenia. RT was found to be effective in increasing strength and muscle mass in older adults diagnosed with osteosarcopenia, though it did not significantly improve physical performance.

Conclusion

There are few studies on this topic, making it difficult to draw definitive conclusions regarding the effectiveness of physical exercise in older adults with osteosarcopenia. Resistance training showed positive results, particularly in improving strength and muscle mass. PROSPERO REGISTRATION NUMBER: https://www.crd.york.ac.uk/PROSPERO/view/CRD42020215659.

至 Europe PMC 閱讀完整來源 ↗ · 擷取日期 2026-10-19

書目、來源與全文狀態
DOI
10.1016/j.gerinurse.2026.103878
PMID/PMCID
41637773
作者
Silveira EA, Souza GVE, Rodrigues LP, Rezende ATO, Romeiro AMS, Noll M, de Oliveira C
首次發表日期
2026-02-04Europe PMC 提供,部分日期可能依年份或月份推定。
卷/期/頁碼或文章編號
69 / 期未提供 / 103878
書目來源與查核日期
Europe PMC · 2026-10-19僅核對書目欄位與來源連結;不代表已評讀研究品質。
全文與授權
來源尚未確認免費全文。 來源授權標示:cc by。

可回溯引用

Silveira EA, Souza GVE, Rodrigues LP, Rezende ATO, Romeiro AMS, Noll M, de Oliveira C. Effectiveness of physical exercise on osteosarcopenia in older adults: A systematic review. Geriatric nursing (New York, N.Y.). 2026;69:103878. PMID: 41637773. doi:10.1016/j.gerinurse.2026.103878

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