The American journal of sports medicine · 2026 · 系統性回顧＋統合分析（依標題推測）

No Evidence of Superior Graft Remodeling and Maturation When Adding a Lateral Extra-articular Procedure to Anterior Cruciate Ligament Reconstruction: A Systematic Review and Meta-analysis of Comparative Studies

膝 · 前十字韌帶損傷

中文閱讀摘要

系統性回顧與統合分析顯示，ACLR加做LEAP與單獨ACLR之移植物SNQ無顯著差異，結果不一致，LEAP不影響移植物成熟。

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原始摘要

Background

The use of postoperative magnetic resonance imaging (MRI) to investigate the effect of concomitant lateral extra-articular procedures (LEAPs) is not well documented in the literature. Few studies have assessed the MRI signal intensity-measured by the signal-to-noise quotient (SNQ)-of the anterior cruciate ligament (ACL) graft between individuals who underwent ACL reconstruction (ACLR) with simultaneous LEAP and those who did not. These comparative studies have produced conflicting results, though, which makes the topic particularly relevant.

Purpose

To systematically compare existing evidence on graft maturation by performing a meta-analysis of combined ACLR and LEAP versus isolated ACLR.

Study design

Systematic review and meta-analysis; Level of evidence, 3.

Methods

The methodology adhered to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. The PubMed, Embase, and Cochrane Library databases were searched to identify potentially relevant comparative studies that analyzed postoperative graft maturation, at least 10 months after surgery, using MRI with SNQ after isolated ACL or ACL plus LEAP. The Methodological Index for Non-Randomized Studies was used for quality assessment.

Results

A total of 542 patients were included, with 307 receiving isolated ACLR and 235 undergoing combined ACL plus LEAP. Meta-analysis revealed no statistical difference between the groups regarding SNQ ( P = .574), with a mean difference of -0.58 (95% CI, -2.62 to 1.45). Neither the rank correlation test nor the linear regression test indicated any funnel plot asymmetry ( P = .272 and P = .642 respectively).

Conclusion

Adding a lateral extra articular procedure to ACLR does not improve graft remodeling and maturation. Furthermore, graft maturation is not influenced by the time from surgery, age, or sex. Despite the limited number of studies considered, these findings suggest that a lateral extra-articular procedure does not play a significant role in graft maturation and should be performed selectively.

至 Europe PMC 閱讀完整來源 ↗ · 擷取日期 2026-10-19

書目、來源與全文狀態

DOI: 10.1177/03635465251376662
PMID／PMCID: 41486743 / PMC12916858
作者: D'Ambrosi R, Skopljak E, Albano D, Messina C, Gitto S, Serpi F, Sconfienza LM
首次發表日期: 2026-01-04Europe PMC 提供，部分日期可能依年份或月份推定。
卷／期／頁碼或文章編號: 54 ／ 3 ／ 724-732
書目來源與查核日期: Europe PMC · 2026-10-19僅核對書目欄位與來源連結；不代表已評讀研究品質。
全文與授權: 來源列有免費全文（查核 2026-10-19），未逐篇測試 PDF 下載。來源授權標示：cc by。

可回溯引用

D'Ambrosi R, Skopljak E, Albano D, Messina C, Gitto S, Serpi F, Sconfienza LM. No Evidence of Superior Graft Remodeling and Maturation When Adding a Lateral Extra-articular Procedure to Anterior Cruciate Ligament Reconstruction: A Systematic Review and Meta-analysis of Comparative Studies. The American journal of sports medicine. 2026;54(3):724-732. PMID: 41486743. PMCID: PMC12916858. doi:10.1177/03635465251376662

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