BMC sports science, medicine & rehabilitation · 2026 · 系統性回顧＋統合分析（依標題推測）
Exercise intervention improves the modified Barthel index, Berg balance scale, and Fugl-Meyer assessment of upper limb motor function in stroke patients: a systematic review and meta-analysis.
神經系統疾病復健 · 腦中風
中文閱讀摘要
統合分析顯示運動顯著改善中風患者MBI、BBS及FMA-UE，且上肢功能改善與劑量呈線性關係，建議累積193小時。
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原始摘要
Background and objective
Exercise is a core approach in stroke rehabilitation, yet updated evidence on its effects on the Berg balance scale (BBS), modified Barthel index (MBI), and Fugl-Meyer assessment of upper extremity motor function (FMA-UE) remains limited. This study systematically evaluated the effects of exercise interventions on these three outcomes.
Methods
PubMed, Web of Science, Cochrane Library, and China National Knowledge Infrastructure (CNKI) were searched from January 2015 to March 2025 for randomized controlled trials. Meta-analysis was performed using RevMan 5.4, and a meta-regression analysis was performed to explore the dose‒response relationship between exercise dose and improvements in FMA-UE scores. The minimal clinically important difference (MCID) was used to derive an optimal dose threshold.
Results
Nineteen RCTs involving 1,041 participants were included. Exercise significantly improved the MBI (SMD = 0.95, 95% CI: 0.42-1.49), BBS (SMD = 0.73, 95% CI: 0.24-1.22), and FMA-UE (SMD = 0.62, 95% CI: 0.16-1.07) scores. The meta-regression analysis revealed a linear relationship (MD = 1.5252 + 0.0003 × total dose). The optimal dose threshold for achieving an MCID of 5 points was approximately 11,580 min (193 h).
Conclusions
Exercise improves balance, daily activities, and upper limb function in stroke patients. The proposed "193-hour concept" provides a preliminary cumulative dose target for clinically meaningful upper limb recovery, pending prospective validation. PROSPERO registration: CRD420251272336.
至 Europe PMC 閱讀完整來源 ↗ · 擷取日期 2026-10-19
書目、來源與全文狀態
- DOI
- 10.1186/s13102-026-01764-z
- PMID／PMCID
- 42174719 / PMC13374158
- 作者
- Zou Z, Liu Y, Zhang Z, Zhao R, Gu L
- 首次發表日期
- 2026-05-22Europe PMC 提供，部分日期可能依年份或月份推定。
- 卷／期／頁碼或文章編號
- 18 ／ 1 ／ 329
- 書目來源與查核日期
- Europe PMC · 2026-10-19僅核對書目欄位與來源連結；不代表已評讀研究品質。
- 全文與授權
- 來源列有免費全文（查核 2026-10-19），未逐篇測試 PDF 下載。 來源授權標示：cc by。
可回溯引用
Zou Z, Liu Y, Zhang Z, Zhao R, Gu L. Exercise intervention improves the modified Barthel index, Berg balance scale, and Fugl-Meyer assessment of upper limb motor function in stroke patients: a systematic review and meta-analysis. BMC sports science, medicine & rehabilitation. 2026;18(1):329. PMID: 42174719. PMCID: PMC13374158. doi:10.1186/s13102-026-01764-z
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