Frontiers in public health · 2025 · 系統性回顧+統合分析(依標題推測)
Effects of resistance training on muscle mass, strength, and physical function in older women with sarcopenia: a systematic review and meta-analysis.
高齡・肌少・骨骼健康 · 肌少症
中文閱讀摘要
統合分析顯示阻力訓練顯著提升肌少症老年女性肌力與功能,但對肌肉質量無顯著影響,證據有限。
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原始摘要
Background and objective
Resistance training is widely recommended for sarcopenia, yet evidence in older women remains limited. This study systematically evaluated its effects on muscle mass, strength, and physical function in this population.
Methods
PubMed, Embase, Web of Science, and the Cochrane Central Register of Controlled Trials were searched up to February 2025; the protocol was registered in PROSPERO (CRD420251066233). Meta-analyses were performed using the "meta" package in R under a random-effects model with restricted maximum likelihood estimation. Study quality was assessed using RoB 2, and evidence certainty via GRADE.
Results
Twelve randomized controlled trials involving 518 older women with sarcopenia were included. Resistance training significantly improved handgrip strength (SMD = 0.43, 95% CI: 0.11-0.74), gait speed (SMD = 0.37, 95% CI: 0.09 to 0.64), knee extension strength (SMD = 0.85, 95% CI: 0.37 to 1.33), Timed Up and Go (SMD = -0.68, 95% CI: -0.95 to -0.41), and 30-Second Chair Stand (SMD = 0.52, 95% CI: 0.19 to 0.86), but had no significant effect on skeletal muscle mass index. Subgroup analyses showed that women with sarcopenic obesity achieved greater gains in knee extension strength, while those with sarcopenia alone improved more in gait speed. Mixed resistance training demonstrated a significant advantage in enhancing gait speed.
Conclusion
Resistance training effectively enhances muscle strength and physical function in older women with sarcopenia, though improvements in muscle mass remain uncertain. Further large-scale, long-term studies are needed to confirm these findings and optimize intervention protocols.
至 Europe PMC 閱讀完整來源 ↗ · 擷取日期 2026-10-19
書目、來源與全文狀態
- DOI
- 10.3389/fpubh.2025.1735899
- PMID/PMCID
- 41668861 / PMC12883749
- 作者
- Zhou Y, Wen K, Zhang X, Sun Y
- 首次發表日期
- 2026-01-26Europe PMC 提供,部分日期可能依年份或月份推定。
- 卷/期/頁碼或文章編號
- 13 / 期未提供 / 1735899
- 書目來源與查核日期
- Europe PMC · 2026-10-19僅核對書目欄位與來源連結;不代表已評讀研究品質。
- 全文與授權
- 來源列有免費全文(查核 2026-10-19),未逐篇測試 PDF 下載。 來源授權標示:cc by。
可回溯引用
Zhou Y, Wen K, Zhang X, Sun Y. Effects of resistance training on muscle mass, strength, and physical function in older women with sarcopenia: a systematic review and meta-analysis. Frontiers in public health. 2025;13:1735899. PMID: 41668861. PMCID: PMC12883749. doi:10.3389/fpubh.2025.1735899
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