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Frontiers in rehabilitation sciences · 2026 · 系統性回顧+統合分析(依標題推測)

Effects of physical therapy modalities for early postoperative pain following total knee arthroplasty: a systematic review and network meta-analysis.

膝 · 全膝關節置換術

中文閱讀摘要

全膝置換術後早期疼痛之網路統合分析顯示冷療、肌貼布及電針較對照組有效,但證據確信度低,需謹慎解讀。

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原始摘要

Objective

This study aims to perform a network meta-analysis (NMA) to evaluate and compare the effects of various physical therapy modalities in mitigating early postoperative pain following total knee arthroplasty (TKA).

Methods

This systematic review and NMA was conducted according to PRISMA-NMA guidelines. A comprehensive literature search was conducted across multiple databases, including PubMed, SPORTDiscus, The Cochrane Library, Embase, Web of Science, CINAHL Plus and China National Knowledge Infrastructure, to identify randomized controlled trials (RCTs) assessing the effects of eight physical therapy modalities on early postoperative pain in patients with TKA. Data were synthesized using a frequentist framework, and the outcome was pain reduction, assessed using validated pain scales such as the Visual Analogue Scale.

Results

A total of 42 RCTs involving 3,165 participants were included. The NMA demonstrated that electroacupuncture, manual lymphatic drainage (MLD), kinesio taping and cryotherapy all significantly alleviated early postoperative pain following TKA compared to controls. Effect sizes [standardized mean differences (SMDs)] ranged from -0.57 [95% confidence interval (CI): -1.12 to -0.01] for MLD to -0.98 (95% CI: -1.50 to -0.45) for cryotherapy. Among these physical therapy modalities, cryotherapy showed the highest probability of being ranked among the more effective interventions (Surface under the cumulative ranking curve = 88.0%), followed by kinesio taping (83.1%) and electroacupuncture (64.0%). Among these interventions, electroacupuncture (SMD = -0.59, 95% CI: -1.19 to 0.00), kinesio taping (SMD = -0.86, 95% CI: -1.54 to -0.18) and cryotherapy (SMD = -0.95, 95% CI: -1.59 to -0.31) demonstrated significant pain reduction compared to continuous passive motion. However, the overall certainty of evidence ranged from low to very low for most comparisons.

Conclusion

This NMA suggests that cryotherapy may be the most effective physical therapy modality for early postoperative pain relief after TKA, followed by kinesio taping and electroacupuncture. However, these findings should be interpreted with caution due to the overall low to very low certainty of evidence and potential risk of bias in the included studies. Further high-quality RCTs are needed to confirm these results and strengthen the evidence base for clinical decision-making.

Systematic review registration

https://www.crd.york.ac.uk/PROSPERO/view/CRD42024518900 identifier CRD42024518900.

至 Europe PMC 閱讀完整來源 ↗ · 擷取日期 2026-10-19

書目、來源與全文狀態
DOI
10.3389/fresc.2026.1780374
PMID/PMCID
42327852 / PMC13279041
作者
Guo C, Fang Z, Han B, Chen Y, Han Q, Tang W, Zhuang L, Liu Y, Qiang M, Huang P, Pan H
首次發表日期
2026-06-05Europe PMC 提供,部分日期可能依年份或月份推定。
卷/期/頁碼或文章編號
7 / 期未提供 / 1780374
書目來源與查核日期
Europe PMC · 2026-10-19僅核對書目欄位與來源連結;不代表已評讀研究品質。
全文與授權
來源列有免費全文(查核 2026-10-19),未逐篇測試 PDF 下載。 來源授權標示:cc by。

可回溯引用

Guo C, Fang Z, Han B, Chen Y, Han Q, Tang W, Zhuang L, Liu Y, Qiang M, Huang P, Pan H. Effects of physical therapy modalities for early postoperative pain following total knee arthroplasty: a systematic review and network meta-analysis. Frontiers in rehabilitation sciences. 2026;7:1780374. PMID: 42327852. PMCID: PMC13279041. doi:10.3389/fresc.2026.1780374

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