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Frontiers in sports and active living · 2026 · 統合分析(依標題推測)

Short-term effects of exercise therapy on pulmonary function and exercise tolerance in patients with mild to moderate adolescent idiopathic scoliosis: a meta-analysis of randomized controlled trial

胸椎 · 青少年特發性脊柱側彎

中文閱讀摘要

統合分析顯示,運動治療短期顯著改善輕中度青少年特發性脊柱側彎患者的肺活量與呼吸肌力量,但證據有限。

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原始摘要

Objective

This meta-analysis aimed to evaluate the effects of exercise therapy on pulmonary function and exercise tolerance in patients with mild to moderate adolescent idiopathic scoliosis (AIS).

Methods

We systematically searched PubMed, Embase, Medline, Web of Science, and Cochrane Library from inception to April 1st, 2025. We included randomized controlled trials (RCTs) enrolling participants with mild to moderate AIS (Cobb angle 10-40°). Data were extracted for the following outcomes: forced expired volume in 1 s (FEV 1 ), forced vital capacity (FVC), FEV₁/FVC ratio, peak expiratory flow (PEF), maximal expiratory pressure (MEP), maximal inspiratory pressure (MIP), and the six-minute walking test (6MWT). The Cochrane systematic review tool was used to assess the methodological quality of the RCTs, and the GRADE approach was applied to evaluate the quality of evidence.

Results

Of 912 screened records, six RCTs involving 224 patients were included. All studies were judged to have a low risk of bias. Compared with control, exercise therapy improved FEV 1 (MD = 0.41 L, 95% CI: 0.22 to 0.59, P < 0.001), FVC (SMD = 0.40 L, 95% CI: 0.02 to 0.78, P < 0.01), FEV1/FVC ratio compared to the control interventions (SMD = 0.46, 95% CI: 0.05 to 0.86, I2: 48%, P < 0.05), MEP (MD = 10.70 cmH₂O, 95% CI: 3.27 to 18.13, P < 0.01), and MIP (MD = 16.44 cmH₂O, 95% CI: 6.87 to 26.01, P < 0.001). Although the subgroup sample size is limited and needs to be interpreted with caution, preliminary results show that long-term (more than 8 weeks) interventions have significant improvement effects on both FEV 1 and FVC, while a single long-term (more than 60 min) intervention only shows significant benefits on FEV 1 .

Conclusions

Exercise therapy can effectively improve lung volumes and enhance respiratory muscle strength in patients with AIS in short term. Therefore, further high-quality RCTs are warranted to confirm these findings.

Systematic review registration

PROSPERO CRD420251034100.

至 Europe PMC 閱讀完整來源 ↗ · 擷取日期 2026-10-19

書目、來源與全文狀態
DOI
10.3389/fspor.2026.1804651
PMID/PMCID
42389152 / PMC13319063
作者
Xie Y, Xie S, Yang J, Yu Q, Zhang G, Feng Y, Liu J, Ye C, Gong H, Wang C, He F
首次發表日期
2026-06-17Europe PMC 提供,部分日期可能依年份或月份推定。
卷/期/頁碼或文章編號
8 / 期未提供 / 1804651
書目來源與查核日期
Europe PMC · 2026-10-19僅核對書目欄位與來源連結;不代表已評讀研究品質。
全文與授權
來源列有免費全文(查核 2026-10-19),未逐篇測試 PDF 下載。 來源授權標示:cc by。

可回溯引用

Xie Y, Xie S, Yang J, Yu Q, Zhang G, Feng Y, Liu J, Ye C, Gong H, Wang C, He F. Short-term effects of exercise therapy on pulmonary function and exercise tolerance in patients with mild to moderate adolescent idiopathic scoliosis: a meta-analysis of randomized controlled trial. Frontiers in sports and active living. 2026;8:1804651. PMID: 42389152. PMCID: PMC13319063. doi:10.3389/fspor.2026.1804651

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