Frontiers in sports and active living · 2026 · 系統性回顧＋統合分析（依標題推測）
Optimal exercise prescription for patients with coronary heart disease across cardiac rehabilitation phases: a systematic review and network meta-analysis
心血管・呼吸・內科 · 冠狀動脈疾病
中文閱讀摘要
系統性回顧與網路統合分析顯示，冠狀動脈疾病患者各復健階段運動處方效果不同，一期證據有限，二三期各有優勢，支持分階段處方。
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原始摘要
Background
Exercise-based cardiac rehabilitation is delivered across distinct clinical phases, yet the optimal exercise modality for improving cardiorespiratory fitness and functional capacity may differ by phase. This systematic review and network meta-analysis compared the relative effects of common exercise modalities on peak oxygen uptake (VO 2 peak) and 6-min walk distance (6MWD) in patients with coronary heart disease across rehabilitation phases.
Methods
English and Chinese databases were searched from inception to April 30, 2026. Randomized controlled trials enrolling adults with coronary heart disease and evaluating exercise interventions were eligible. Two reviewers independently screened studies, extracted data, and assessed risk of bias using the Cochrane risk-of-bias tool. A frequentist network meta-analysis synthesized direct and indirect evidence within each phase (phase I inpatient, phase II early outpatient, phase III long-term maintenance). Continuous outcomes were pooled as mean differences with 95% confidence intervals (VO 2 peak in mL·kg⁻¹·min⁻¹; 6MWD in meters). Global inconsistency testing guided the use of consistency vs. inconsistency models. Interventions were ranked using the surface under the cumulative ranking curve (SUCRA).
Results
Eighty-seven trials (7,241 participants) were included, covering aerobic exercise (AE), resistance training (RT), combined aerobic plus resistance training (AE + RT), high-intensity interval training (HIIT), traditional Chinese exercise (TCE; e.g., Tai Chi/qigong/Baduanjin), aerobic exercise combined with traditional Chinese exercise (AE + TCE), and conventional therapy (CT). Evidence was phase-imbalanced (9 phase I, 39 phase II, and 40 phase III trials); one study contributed outcomes to both Phase II and Phase III analyses. In phase I, evidence was comparatively limited; for VO 2 peak TCE and AE showed the most favorable probability of benefit vs. CT. Phase II provided the most informative network for VO 2 peak with RT and HIIT ranking highest, followed by AE + TCE. In phase III, for 6MWD, AE + RT ranked highest, with AE and TCE also showing favorable ranking; for VO 2 peak maintenance-phase signals favored RT- and combined-training-based approaches.
Conclusions
The relative effectiveness of exercise modalities appears phase-dependent. These findings support phase-tailored exercise prescription in coronary heart disease, while emphasizing the need for additional head-to-head trials-particularly in early inpatient rehabilitation-to strengthen comparative evidence.
Systematic review registration
https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD420251156834, PROSPERO, identifier CRD420251156834.
至 Europe PMC 閱讀完整來源 ↗ · 擷取日期 2026-10-19
書目、來源與全文狀態
- DOI
- 10.3389/fspor.2026.1813426
- PMID／PMCID
- 42367338 / PMC13294071
- 作者
- Qiao C, Yang S, Wang Y
- 首次發表日期
- 2026-06-11Europe PMC 提供，部分日期可能依年份或月份推定。
- 卷／期／頁碼或文章編號
- 8 ／ 期未提供 ／ 1813426
- 書目來源與查核日期
- Europe PMC · 2026-10-19僅核對書目欄位與來源連結；不代表已評讀研究品質。
- 全文與授權
- 來源列有免費全文（查核 2026-10-19），未逐篇測試 PDF 下載。 來源授權標示：cc by。
可回溯引用
Qiao C, Yang S, Wang Y. Optimal exercise prescription for patients with coronary heart disease across cardiac rehabilitation phases: a systematic review and network meta-analysis. Frontiers in sports and active living. 2026;8:1813426. PMID: 42367338. PMCID: PMC13294071. doi:10.3389/fspor.2026.1813426
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